Description

(Diacetyl)-α-Msh CAS NO 71952-90-4 is a chemically modified derivative of the α-melanocyte-stimulating hormone (α-MSH) peptide, where diacetyl groups have been introduced to enhance its stability or alter its biological activity profile. This modification is of significant interest in advanced pharmaceutical research and development, particularly for exploring novel therapeutic pathways. It serves as a critical intermediate or reference standard for researchers and manufacturers in the fields of endocrinology, dermatology, and metabolic disorder studies.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel peptide-based therapeutics targeting melanocortin receptors.
• Biochemical Reference Standard: Used for analytical method development, validation, and quality control in peptide manufacturing.
• Academic & Clinical Studies: Employed in preclinical research to investigate the structure-activity relationships (SAR) of modified MSH peptides and their effects on pigmentation, inflammation, and energy homeostasis.
• Peptide Library Synthesis: A valuable building block for creating specialized peptide libraries for high-throughput screening in drug discovery.
• Cosmeceutical R&D: Investigated for potential applications in skin pigmentation modulation and related dermatological conditions.

Basic Information

Product Name	(Diacetyl)-α-Msh
CAS No.	71952-90-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Diacetyl-α-MSH; N-α-acetyl-α-MSH; Acetylated α-Melanocyte Stimulating Hormone; α-MSH diacetate; [Acetyl]-α-MSH; Melanotropin (α-) diacetate; Ac-α-MSH; SYSMEHFRWGKPV-NH2 (diacetylated)
EINECS	Contact for details

Quality Control

Our (Diacetyl)-α-Msh is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for research and development purposes. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. While typically supplied as a research-grade chemical, production can be aligned with cGMP guidelines for advanced applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.