Description

2-Fluoro-4-Chlorobenzyl Bromide is a versatile and highly reactive halogenated benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the 2-fluoro-4-chlorobenzyl moiety into target molecules, enabling the development of compounds with tailored biological and physical properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine and chlorine substituents enhance bioactivity and environmental stability.
• Liquid Crystal & OLED Material Production: Serves as a building block for synthesizing fluorinated and chlorinated aromatic compounds used in electronic display technologies.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for constructing complex biaryl structures.
• Functional Material Research: Employed in organic chemistry R&D to create novel ligands, polymers, and dyes with specific electronic characteristics.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Fluoro-4-Chlorobenzyl Bromide
CAS No.	71916-82-0
Molecular Formula	C7H5BrClF
Molecular Weight	223.47 g/mol
Synonyms	1-(Bromomethyl)-2-fluoro-4-chlorobenzene; (2-Fluoro-4-chlorophenyl)methyl Bromide; α-Bromo-2-fluoro-4-chlorotoluene; 2-Fluoro-4-chlorobenzyl Bromide; 2-Fluoro-4-chloro-α-bromotoluene; 4-Chloro-2-fluorobenzyl Bromide; Benzene, 1-(bromomethyl)-2-fluoro-4-chloro-; Bromo(2-fluoro-4-chlorophenyl)methane
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Chlorobenzyl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.