Description

S-Adenosyl-L-Methionine Tosylate is a stabilized salt form of the critical biological cofactor and methyl donor, S-adenosylmethionine (SAMe). This high-purity compound is essential for research and production in life sciences, offering superior stability and handling characteristics compared to other salt forms. It is a key material for pharmaceutical development, biochemical research, and the manufacture of high-value nutraceuticals targeting liver health, joint function, and mood regulation.

Application

• Pharmaceutical Active Ingredient (API): Core component in prescription and over-the-counter formulations for hepatoprotective, antidepressant, and osteoarthritis treatments.
• Nutraceutical & Dietary Supplement Manufacturing: Used as the active compound in capsules, tablets, and powders for liver support, joint health, and cognitive/mood enhancement products.
• Biochemical & Life Science Research: Essential substrate for studying methylation processes, enzyme kinetics (methyltransferases), and cellular metabolism in vitro.
• Reference Standard & Analytical Testing: Serves as a certified reference material (CRM) for quality control and assay development in pharmaceutical and supplement industries.
• Cell Culture & Microbiology: Added to media to support methylation-dependent pathways in specialized cell culture and microbial fermentation processes.
• Precursor for Specialty Chemicals: Intermediate in the synthesis of more complex methylated compounds and advanced biochemicals.

Basic Information

Item	Detail
Product Name	S-Adenosyl-L-Methionine Tosylate
CAS No.	71914-80-2
Molecular Formula	C21H29N6O11S2 • C7H8O3S
Molecular Weight	766.80 g/mol
Synonyms	S-Adenosylmethionine Tosylate; SAMe Tosylate; AdoMet Tosylate; Ademetionine Tosylate; (2S)-2-Amino-4-[[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate 4-methylbenzenesulfonate; SAM Tosylate; L-SAM Tosylate; S-Adenosyl-L-Methionine p-Toluenesulfonate Salt
EINECS	Contact for details

Quality Control

Our S-Adenosyl-L-Methionine Tosylate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent testing, to ensure it meets stringent specifications for pharmaceutical and nutraceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm
Total Impurities (HPLC)	≤ 2.0%
Microbial Limits	Meets USP/EP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.