Description

2-(Acetylamino)Benzenesulfonyl Chloride is a high-purity sulfonyl chloride derivative, a key reactive intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile building block for constructing complex molecules with sulfonamide linkages, which are critical in numerous high-performance applications. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of sulfonamide-based drug candidates, including protease inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that require the sulfonamide pharmacophore.
• Dye and Pigment Manufacturing: Serves as a reactive moiety for introducing sulfonyl groups into dye molecules, enhancing properties like solubility and color fastness.
• Polymer Modification: Employed to functionalize polymers and resins, imparting specific chemical resistance or surface activity.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry research to explore new synthetic pathways.
• Ligand and Catalyst Preparation: Used in the synthesis of specialized ligands for metal catalysis and molecular recognition.

Basic Information

Product Name	2-(Acetylamino)Benzenesulfonyl Chloride
CAS No.	71905-93-6
Molecular Formula	C8H8ClNO3S
Molecular Weight	233.67 g/mol
Synonyms	N-Acetylsulfanilyl Chloride; 2-Acetamidobenzenesulfonyl Chloride; o-Acetamidobenzenesulfonyl Chloride; 2-(Acetylamino)benzenesulfonyl chloride; 2-Acetamidophenylsulfonyl Chloride; Acetylsulfanilyl Chloride; N-(2-Chlorosulfonylphenyl)acetamide
EINECS	Contact for details

Quality Control

Our 2-(Acetylamino)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.