Description

H-Pro-Ser-Oh CAS NO 71835-80-8 is a high-purity, protected dipeptide building block, specifically L-Prolyl-L-serine. This compound is a critical intermediate for the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Pharmaceutical Intermediate: Key building block for the solid-phase and solution-phase synthesis of therapeutic peptides targeting metabolic disorders, neurological conditions, and oncology.
• Biochemical Research: Used in structure-activity relationship (SAR) studies and as a standard in analytical method development for peptide characterization.
• Peptidomimetic Development: Serves as a core scaffold for designing and synthesizing non-natural peptide analogs with enhanced stability and bioavailability.
• Cosmetic Peptide Synthesis: A precursor for bioactive peptides used in advanced skincare formulations for anti-aging and skin repair applications.
• Enzyme Substrate & Inhibitor Design: Utilized in the development of specific substrates or inhibitors for proteases and other enzymes.

Basic Information

Product Name	H-Pro-Ser-Oh
CAS No.	71835-80-8
Molecular Formula	C8H14N2O4
Molecular Weight	202.21 g/mol
Synonyms	L-Prolyl-L-serine; Pro-Ser; H-Pro-Ser-OH; Pro-Ser Dipeptide; (2S)-2-[[(2S)-Pyrrolidine-2-carbonyl]amino]-3-hydroxypropanoic Acid; Boc-Pro-Ser-OH (when protected); Fmoc-Pro-Ser-OH (when protected); 71835-80-8
EINECS	Contact for details

Quality Control

Our H-Pro-Ser-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via mass spectrometry and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and cGMP-grade production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.