Description

L-Alloisoleucinemethylesterhydrochloride CAS NO 71776-74-4 is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block, enabling the precise construction of complex peptides and other bioactive molecules. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the development of novel therapeutics and specialized chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) for the controlled incorporation of the L-alloisoleucine residue.
• Biochemical Research: Employed in the study of protein structure-function relationships and enzyme-substrate interactions.
• Proteomics & Diagnostics: Acts as a component in the synthesis of specialized peptides used as standards, probes, or diagnostic tools.
• Fine Chemical Synthesis: Utilized as a versatile intermediate for constructing complex natural products and other non-peptide chiral molecules.

Basic Information

Product Name	L-Alloisoleucinemethylesterhydrochloride
CAS No.	71776-74-4
Molecular Formula	C7H16ClNO2
Molecular Weight	181.66 g/mol
Synonyms	L-Alloisoleucine methyl ester hydrochloride; (2S,3S)-2-Amino-3-methylpentanoic acid methyl ester hydrochloride; Methyl (2S,3S)-2-amino-3-methylpentanoate hydrochloride; Methyl L-alloisoleucinate hydrochloride; allo-Ile-OMe·HCl; (2S,3S)-Isoleucine methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our L-Alloisoleucinemethylesterhydrochloride is manufactured under strict quality control protocols to ensure high chemical purity and chiral integrity, suitable for demanding research and development applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable to ensure consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.