Description

R(-)-Denopamine is the single enantiomer form of the β-1 adrenergic receptor agonist Denopamine. This high-purity chiral compound is critical for advanced pharmaceutical research and development, particularly in the study of cardiac function. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel cardiovascular therapeutics and in-depth pharmacological studies. The specific stereochemistry of R(-)-Denopamine CAS NO 71771-90-9 makes it an essential reference standard and a key intermediate for targeted drug discovery.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for analytical method development, validation, and quality control in API manufacturing.
• Cardiovascular Research: Serves as a key pharmacological tool for in vitro and in vivo studies targeting β-1 adrenergic receptors to investigate cardiac contractility and heart failure pathways.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed as a critical chiral building block in the synthetic route for developing new enantiomerically pure cardiovascular drugs.
• Biochemical Assay Development: Utilized in high-throughput screening (HTS) assays and binding studies to identify and characterize new receptor modulators.
• Metabolite and Impurity Synthesis: Acts as a starting material for the synthesis of related metabolites or degradation products for toxicological and stability testing.

Basic Information

Product Name	R(-)-Denopamine
CAS No.	71771-90-9
Molecular Formula	C18H23NO4
Molecular Weight	317.38 g/mol
Synonyms	(-)-Denopamine; (R)-Denopamine; (R)-(-)-Denopamine; TA-064; (R)-α-[[(3,4-Dimethoxyphenethyl)amino]methyl]-4-hydroxybenzyl alcohol; 1-(4-Hydroxyphenyl)-2-[[(3,4-dimethoxyphenethyl)amino]methyl]ethanol (R)-
EINECS	Contact for details

Quality Control

Our R(-)-Denopamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess. We support compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.