Description

4(1H)-Quinazolinone, 6,7,8-Trimethoxy-2-(4-Methoxyphenyl)- (9Ci) is a high-purity, multi-methoxylated quinazolinone derivative, a privileged scaffold in medicinal chemistry. This compound matters as a key synthetic intermediate for developing novel pharmaceutical agents, offering a versatile building block for targeted molecular synthesis. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in drug discovery programs, particularly those focused on kinase inhibitors and other therapeutic small molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Employed in vitro to study enzyme inhibition and cellular signaling pathways.
• Fine Chemical Synthesis: Acts as a specialized building block for constructing complex heterocyclic compounds in custom synthesis projects.
• Reference Standard: Used as an analytical standard in quality control and method development for related pharmaceutical products.

Basic Information

Product Name	4(1H)-Quinazolinone, 6,7,8-Trimethoxy-2-(4-Methoxyphenyl)- (9Ci)
CAS No.	71628-70-1
Molecular Formula	C₁₈H₁₈N₂O₅
Molecular Weight	342.35 g/mol
Synonyms	6,7,8-Trimethoxy-2-(4-methoxyphenyl)quinazolin-4(1H)-one; 2-(4-Methoxyphenyl)-6,7,8-trimethoxy-4(1H)-quinazolinone; 6,7,8-Trimethoxy-2-(4-methoxyphenyl)-1,4-dihydroquinazolin-4-one; 2-(p-Methoxyphenyl)-6,7,8-trimethoxy-4(1H)-quinazolinone; 4(1H)-Quinazolinone, 6,7,8-trimethoxy-2-(4-methoxyphenyl)-; 71628-70-1; CCRIS 9351
EINECS	Contact for details

Quality Control

Our 4(1H)-Quinazolinone, 6,7,8-Trimethoxy-2-(4-Methoxyphenyl)- (9Ci) is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled and stored accordingly to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.