Description

Parathyroid Hormone (1-30) is a synthetic peptide fragment corresponding to the biologically active N-terminal region of the full-length parathyroid hormone. This compound is a critical research tool for studying calcium and phosphate metabolism, bone remodeling, and renal function. It is essential for pharmaceutical R&D, academic research in endocrinology, and the development of diagnostic assays and therapeutic candidates for bone-related disorders.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) in the development of treatments for osteoporosis, hypoparathyroidism, and other metabolic bone diseases.
• Biochemical & Physiological Studies: Serves as a key reagent to investigate PTH receptor (PTH1R) signaling pathways, hormone-receptor interactions, and downstream cellular effects.
• Diagnostic Assay Development: Employed as a calibrator or control in the development of immunoassays (e.g., ELISA, RIA) for measuring PTH levels in clinical and research settings.
• Academic & Preclinical Research: A fundamental tool for in vitro and in vivo studies exploring calcium homeostasis, bone formation/resorption, and the endocrine functions of the parathyroid gland.
• Peptide Chemistry & Conjugation: Acts as a substrate for studying peptide stability, modification, and for creating labeled derivatives (e.g., fluorescent, biotinylated) for various detection methods.

Basic Information

Item	Detail
Product Name	Parathyroid Hormone (1-30)
CAS No.	71512-77-1
Molecular Formula	C₁₄₈H₂₄₀N₄₄O₄₈S₂
Molecular Weight	~3341.8 g/mol
Synonyms	PTH (1-30); Human Parathyroid Hormone (1-30); hPTH(1-30); Parathyrin (1-30); N-terminal Parathyroid Hormone Fragment; Teriparatide Fragment (1-30); PTH 1-30 amide (human); CAS 71512-77-1
EINECS	Contact for details

Quality Control

Our Parathyroid Hormone (1-30) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) detailing purity, peptide content, and residual solvent levels, ensuring compliance with rigorous research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.