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Adp-Ribosylarginine CAS NO 71388-78-8
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CAS No.:71388-78-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Adp-Ribosylarginine is a specialized biochemical compound of significant interest in life science research. This molecule plays a crucial role in the study of post-translational modifications, specifically ADP-ribosylation, which is a key regulatory mechanism in cellular processes. It is an essential reference standard and research reagent for scientists in the fields of molecular biology, enzymology, and signal transduction. Researchers in pharmaceutical development and academic institutions utilize this high-purity compound to investigate protein function, disease mechanisms, and potential therapeutic targets.
Application
- Biochemical Research: Serves as a critical reference standard and substrate in studies of ADP-ribosyltransferase and glycohydrolase enzymes.
- Enzymology Studies: Used to investigate the kinetics, specificity, and mechanisms of arginine-specific ADP-ribosylation reactions.
- Signal Transduction Research: A key tool for elucidating the role of mono-ADP-ribosylation in cellular signaling pathways and protein regulation.
- Pharmaceutical Development: Employed in target validation and screening assays for drug discovery programs focused on ADP-ribosylation-related diseases.
- Diagnostic Reagent Development: Used in the development and calibration of assays designed to detect or quantify ADP-ribosylated proteins.
- Academic Research: Essential for fundamental research in cell biology, cancer biology, and neurobiology to understand post-translational modifications.
Basic Information
| Item | Details |
|---|---|
| Product Name | Adp-Ribosylarginine |
| CAS No. | 71388-78-8 |
| Molecular Formula | C17H26N8O13P2 |
| Molecular Weight | 636.39 g/mol |
| Synonyms | ADP-Ribosyl-L-arginine; Nω-(ADP-Ribosyl)-L-arginine; L-Arginine, Nω-[1-(5-O-phosphono-β-D-ribofuranosyl)-1H-1,2,3-triazol-4-yl]adenin-9-yl ester; ADP-Ribosyl Arg; Mono(ADP-ribosyl)arginine; Arginine ADP-ribose; ADPR-Arg |
| EINECS | Contact for details |
Quality Control
Our Adp-Ribosylarginine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is thoroughly characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, ensuring full traceability and compliance with research-grade standards.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under an inert atmosphere to maintain stability. Allow the product to equilibrate to room temperature before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 5.0% |
| Heavy Metals | ≤ 20 ppm |
| Solubility | Soluble in water, DMSO |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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