Description

2,2-Diphenylethanesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key building block in organic synthesis. Its value lies in its role as a versatile sulfonylation reagent, enabling the introduction of the diphenylethanesulfonyl protecting group or functional moiety. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Serves as a critical reagent in the synthesis of potential drug candidates, particularly for introducing sulfonamide groups.
• Peptide Chemistry: Used as a protecting group reagent for amines during complex peptide synthesis.
• Agrochemical Synthesis: Employed in the research and development of new herbicides, fungicides, and insecticides.
• Material Science Research: Acts as a monomer or modifying agent in the development of specialty polymers and advanced materials.
• Chemical Biology Probes: Utilized to create sulfonylated probes for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2,2-Diphenylethanesulfonyl Chloride
CAS No.	71351-01-4
Molecular Formula	C14H13ClO2S
Molecular Weight	280.77 g/mol
Synonyms	2,2-Diphenylethanesulfonyl chloride; 1-Chlorosulfonyl-2,2-diphenylethane; 2,2-Diphenylethane-1-sulfonyl chloride; α-Phenylbenzenesulfonyl chloride; Diphenylethanesulfonyl chloride; (2,2-Diphenylethyl)sulfonyl chloride; Benzenemethanesulfonyl chloride, α-phenyl-; EINECS 275-325-5
EINECS	275-325-5

Quality Control

Our 2,2-Diphenylethanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.