Description

5-Trifluoromethyl-2-Oxindole is a high-value, fluorinated heterocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring a trifluoromethyl group on the oxindole scaffold, makes it indispensable for modulating the physicochemical properties and biological activity of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science: Serves as a precursor for functionalized organic molecules used in organic light-emitting diodes (OLEDs) and other electronic materials.
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and the exploration of new fluorination chemistry.

Basic Information

Product Name	5-Trifluoromethyl-2-Oxindole
CAS No.	71293-62-4
Molecular Formula	C9H4F3NO2
Molecular Weight	215.13 g/mol
Synonyms	5-(Trifluoromethyl)-1,3-dihydro-2H-indol-2-one; 5-(Trifluoromethyl)oxindole; 2-Oxindole, 5-(trifluoromethyl)-; 5-Trifluoromethyloxindole; 5-Trifluoromethyl-2-indolinone; 1,3-Dihydro-5-(trifluoromethyl)-2H-indol-2-one
EINECS	Contact for details

Quality Control

Every batch of 5-Trifluoromethyl-2-Oxindole is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.