Description

H-Pro-Lys-Oh CAS NO 71227-70-8 is a protected dipeptide derivative, specifically the Cbz-protected form of Prolyl-Lysine. This compound serves as a crucial high-purity building block in peptide synthesis, offering precise control over the amino acid sequence. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers for developing novel therapeutic peptides and biochemical tools.

Application

• Pharmaceutical Intermediate: Key raw material in the solid-phase and solution-phase synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or reagent in proteomics research, enzyme substrate studies, and metabolic pathway investigations.
• Peptide Library Construction: Essential component for generating combinatorial peptide libraries for drug discovery and high-throughput screening.
• Cosmetic Peptide Synthesis: Building block for synthesizing specialized peptides used in advanced skincare and cosmetic formulations.
• Academic & Industrial R&D: Serves as a critical reagent in university and corporate laboratories for exploring new peptide structures and functions.

Basic Information

Product Name	H-Pro-Lys-Oh
CAS No.	71227-70-8
Molecular Formula	C17H25N3O5
Molecular Weight	351.40 g/mol
Synonyms	Nα-Cbz-L-Prolyl-L-lysine; N-Carbobenzoxy-Prolyl-Lysine; Z-Pro-Lys-OH; CBZ-Pro-Lys; (S)-2-(((S)-1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-guanidinopentyl)amino)-3-phenylpropanoic acid (related protected form); Prolyllysine, Nα-benzyloxycarbonyl-; L-Lysine, N2-[(phenylmethoxy)carbonyl]-L-prolyl-; Fmoc-Lys(Z)-OH (common precursor/related compound)
EINECS	Contact for details

Quality Control

Our H-Pro-Lys-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to ensure stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.