Description

Gly-Gly-D-Leu CAS NO 71184-74-2 is a synthetic dipeptide derivative, specifically the D-isomer of the leucine-containing sequence. This compound serves as a crucial building block and chiral intermediate in advanced organic synthesis and peptide research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for developing novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and protease inhibitors.
• Biochemical Research: Used in enzymatic studies and as a substrate analog to investigate peptide metabolism and transport mechanisms.
• Peptide Library Construction: Employed in combinatorial chemistry for creating diverse peptide libraries to screen for biological activity.
• Asymmetric Synthesis: Leverages the D-configuration of leucine for constructing complex, stereochemically defined molecules.
• Reference Standard: Serves as an analytical standard in quality control for peptide manufacturing.

Basic Information

Product Name	Gly-Gly-D-Leu
CAS No.	71184-74-2
Molecular Formula	C10H19N3O4
Molecular Weight	245.28 g/mol
Synonyms	Glycyl-glycyl-D-leucine; D-Leucine, glycylglycyl-; H-Gly-Gly-D-Leu-OH; (R)-2-(2-(2-Aminoacetamido)acetamido)-4-methylpentanoic acid; Gly-Gly-D-Leucine; GGDLeu; Glycylglycyl-D-leucine; N-Glycylglycyl-D-leucine
EINECS	Contact for details

Quality Control

Our Gly-Gly-D-Leu is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Specific range available on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.