Description

4-Pyrimidinecarboxaldehyde, 1,2-Dihydro-2-Thioxo- (9Ci) is a specialized heterocyclic building block featuring a reactive aldehyde group adjacent to a thioxo moiety on a dihydropyrimidine core. This unique molecular architecture makes it a critical intermediate for synthesizing complex pharmacologically active compounds and advanced materials. It is primarily utilized by research institutions and pharmaceutical R&D departments engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing libraries of compounds for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique properties.
• Academic Research: Fundamental studies in heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	4-Pyrimidinecarboxaldehyde, 1,2-Dihydro-2-Thioxo- (9Ci)
CAS No.	71183-60-3
Molecular Formula	C5H4N2OS
Molecular Weight	140.16 g/mol
Synonyms	2-Thioxo-1,2-dihydropyrimidine-4-carboxaldehyde; 4-Formyl-2-mercaptopyrimidine; 2-Mercaptopyrimidine-4-carboxaldehyde; 1,2-Dihydro-2-thioxopyrimidine-4-carboxaldehyde; 2-Thioxo-1,2-dihydro-4-pyrimidinecarboxaldehyde; 4-Pyrimidinecarboxaldehyde, 1,2-dihydro-2-thioxo-; 2-Mercapto-4-pyrimidinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-Pyrimidinecarboxaldehyde, 1,2-Dihydro-2-Thioxo- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.