Description

L-Histidine Monoacetate is a high-purity, crystalline salt form of the essential amino acid L-Histidine, offering enhanced stability and handling characteristics. This compound is critical for applications requiring a bioavailable source of histidine with improved solubility and reduced hygroscopicity compared to the free base. It serves as a vital raw material and intermediate for manufacturers in the pharmaceutical, nutraceutical, and food & beverage industries, where precise ingredient quality is paramount for final product efficacy and safety.

Application

• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) and as a component in parenteral nutrition and infusion solutions.
• Dietary Supplements & Nutraceuticals: A key ingredient in amino acid supplements, protein powders, and clinical nutrition products for its role in protein synthesis and metabolic functions.
• Food & Beverage Fortification: Employed as a nutritional enhancer in specialized foods, medical foods, and sports nutrition products.
• Biochemical Research & Cell Culture: Serves as a defined component in cell culture media, microbiological assays, and enzymatic studies.
• Cosmetic & Personal Care: Incorporated into skincare formulations for its potential role as a moisturizing agent and antioxidant.
• Animal Feed Additives: Used in premium feed formulations to ensure adequate amino acid nutrition for livestock and aquaculture.

Basic Information

Product Name	L-Histidine Monoacetate
CAS No.	71173-63-2
Molecular Formula	C8H11N3O2 • C2H4O2
Molecular Weight	233.23 g/mol
Synonyms	Histidine Acetate; L-Histidine Acetate Salt; (S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid acetate; Histidine Monoacetate; L-Histidine Acetate (1:1); H-His-OH • AcOH; Acetic acid, compd. with L-histidine (1:1)
EINECS	Contact for details

Quality Control

Our L-Histidine Monoacetate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets specifications for identity, purity, and safety, aligning with standards such as USP, EP, and FCC where applicable. A Certificate of Analysis (COA) documenting specific test results is provided with every shipment to guarantee traceability and compliance for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Specific Rotation	+8.5° to +10.5° (c=2, in H2O)
pH (5% solution)	6.5 - 7.5
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.