Description

Ethyl 4-Hydroxypyrimidine-5-Carboxylate is a versatile pyrimidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other high-value fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and antiviral applications.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging the bioactive pyrimidine core.
• Fine Chemical Production: Serves as a building block for creating complex molecules used in materials science and specialty polymers.
• Research & Development: Employed in academic and industrial R&D labs for method development and exploring new chemical entities.
• Chemical Reference Standard: Utilized as a high-purity standard for analytical testing and quality control in manufacturing processes.

Basic Information

Product Name	Ethyl 4-Hydroxypyrimidine-5-Carboxylate
CAS No.	71133-20-5
Molecular Formula	C7H8N2O3
Molecular Weight	168.15 g/mol
Synonyms	5-Carbethoxy-4-hydroxypyrimidine; Ethyl 4-hydroxy-5-pyrimidinecarboxylate; 4-Hydroxypyrimidine-5-carboxylic acid ethyl ester; 5-Ethoxycarbonyl-4-hydroxypyrimidine; 4-Hydroxy-5-pyrimidinecarboxylic acid ethyl ester; Ethyl 4-oxo-3,4-dihydropyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 4-hydroxy-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Hydroxypyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.