Description

(1S)-1α-(β-D-Glucopyranosyloxy)-1,4Aα,5,6,7,7Aα-Hexahydro-5-Oxocyclopenta[C]Pyran-4,7α-Dicarboxylic Acid Dimethyl Ester is a high-purity, complex organic ester with a glucopyranosyl moiety, serving as a critical advanced pharmaceutical intermediate and a valuable scaffold in synthetic organic chemistry. Its unique molecular architecture, combining a cyclopentapyran core with a sugar derivative, makes it an essential building block for the research and development of novel bioactive compounds. This product is primarily targeted at pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of fine chemicals seeking to develop new therapeutic agents or complex molecular entities.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of potential drug candidates, particularly those targeting metabolic or enzymatic pathways.
• Glycoscience Research: Used as a probe or building block in glycosylation studies and the development of glycosidase inhibitors or glycomimetics.
• Medicinal Chemistry: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce complex chiral and functionalized structures into target molecules.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or conjugates for biochemical and diagnostic applications due to its reactive ester groups and sugar component.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in organic synthesis methodology and chemical biology.

Basic Information

Product Name	(1S)-1α-(β-D-Glucopyranosyloxy)-1,4Aα,5,6,7,7Aα-Hexahydro-5-Oxocyclopenta[C]Pyran-4,7α-Dicarboxylic Acid Dimethyl Ester
CAS No.	71035-06-8
Molecular Formula	C₁₉H₂₆O₁₂
Molecular Weight	446.40 g/mol
Synonyms	Dimethyl (1S,4aS,7aR)-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-oxo-1,4a,5,6,7,7a-hexahydro-4H-cyclopenta[c]pyran-4,7-dicarboxylate; 1-(β-D-Glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-5-oxocyclopenta[c]pyran-4,7-dicarboxylic Acid Dimethyl Ester; Glucopyranosyl Cyclopentapyran Dicarboxylate Dimethyl Ester; CAS 71035-06-8
EINECS	Contact for details

Quality Control

Our production of (1S)-1α-(β-D-Glucopyranosyloxy)-1,4Aα,5,6,7,7Aα-Hexahydro-5-Oxocyclopenta[C]Pyran-4,7α-Dicarboxylic Acid Dimethyl Ester adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (NMR, IR, MS), and determination of residual solvents and moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed when not in use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.