Description

Glutaryl-Gly-Gly-Phe-Amc is a synthetic peptide substrate designed for high-precision enzymatic research and diagnostic applications. This compound is critical for studying and quantifying the activity of specific proteolytic enzymes, such as dipeptidyl peptidase IV (DPP-IV) and related serine proteases. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, biotechnology, and clinical diagnostics sectors who require reliable and sensitive assay components.

Application

• Enzyme Activity Assays: Primary substrate for fluorometric or colorimetric assays measuring DPP-IV (CD26) activity in research and drug discovery.
• Pharmaceutical Screening: Used in high-throughput screening (HTS) platforms to identify and characterize inhibitors of target proteases for therapeutic development.
• Clinical Diagnostics: Employed in the development of in-vitro diagnostic (IVD) kits for monitoring enzymatic activity related to specific disease states.
• Biochemical Research: A key reagent for kinetic studies, enzyme characterization, and mechanistic investigations in academic and industrial laboratories.
• Quality Control: Serves as a reference standard in the QC of biopharmaceuticals where protease activity must be controlled or measured.

Basic Information

Product Name	Glutaryl-Gly-Gly-Phe-Amc
CAS No.	70996-06-4
Molecular Formula	C27H31N5O7
Molecular Weight	537.57 g/mol
Synonyms	Glutaryl-Gly-Gly-Phe-7-Amido-4-Methylcoumarin; Glutaryl-Gly-Gly-Phe-AMC; GGP-Amc; GGP-AMC; DPP-IV Substrate (Glutaryl-GGP-Amc); H-Glu-Gly-Gly-Phe-AMC; 7-Amido-4-methylcoumarin conjugate of Glutaryl-Gly-Gly-Phe; Glutaryl-Glycyl-Glycyl-L-Phenylalanine 7-Amido-4-Methylcoumarin
EINECS	Contact for details

Quality Control

Our Glutaryl-Gly-Gly-Phe-Amc is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance in sensitive assays. Each lot is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and related substances are provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.