Description

2,2,2-Trifluoro-1-(2-Hydroxy-5-Methylphenyl)-Ethanone is a specialized fluorinated aromatic ketone that serves as a valuable building block in advanced organic synthesis. Its unique trifluoromethyl and phenolic hydroxyl groups make it a critical intermediate for introducing fluorine atoms into target molecules, enhancing their metabolic stability and lipophilicity. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in creating molecules with trifluoromethyl groups for improved drug properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine moiety can increase biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Advanced Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine into polymer chains, enhancing material properties like chemical resistance and thermal stability.
• Organic Synthesis & Catalysis Research: A versatile reagent in academic and industrial R&D for constructing complex fluorinated aromatic systems and exploring new catalytic pathways.

Basic Information

Product Name	2,2,2-Trifluoro-1-(2-Hydroxy-5-Methylphenyl)-Ethanone
CAS No.	70978-57-3
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	2-Hydroxy-5-methyl-2',2',2'-trifluoroacetophenone; 1-(2-Hydroxy-5-methylphenyl)-2,2,2-trifluoroethanone; 2',2',2'-Trifluoro-2-hydroxy-5'-methylacetophenone; 2,2,2-Trifluoro-1-(2-hydroxy-5-methylphenyl)ethan-1-one; α,α,α-Trifluoro-2-hydroxy-5-methylacetophenone; TFHMP; Trifluoromethyl hydroxy methylphenyl ketone
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(2-Hydroxy-5-Methylphenyl)-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.