Description

5'-Fluoro-2'-Hydroxy-3'-Nitro- is a high-purity, multi-functional aromatic compound characterized by its distinct nitro and fluoro substituents. This versatile intermediate is critical for driving innovation in advanced organic synthesis, enabling the development of novel molecular architectures. It is primarily sought after by research institutions and industrial R&D teams in the pharmaceutical and agrochemical sectors for the synthesis of complex active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro group.
• Dye & Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and pigments where nitro and hydroxy groups contribute to color fastness and chromophore development.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing biaryl structures common in many functional molecules.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	5'-Fluoro-2'-Hydroxy-3'-Nitro-
CAS No.	70978-39-1
Molecular Formula	C6H4FNO3
Molecular Weight	157.10 g/mol
Synonyms	2-Hydroxy-3-nitro-5-fluorobenzene; 5-Fluoro-2-hydroxy-3-nitrobenzene; 3-Nitro-5-fluoro-2-hydroxybenzene; 5-Fluoro-3-nitro-2-phenol; 2-Hydroxy-5-fluoro-3-nitrobenzene; 5-Fluoro-2-phenol-3-nitro; 70978-39-1 (CAS Registry)
EINECS	Contact for details

Quality Control

Our 5'-Fluoro-2'-Hydroxy-3'-Nitro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.