Description

Meosuc-Aapm-Pna is a specialized synthetic organic compound widely utilized as a high-precision chemical intermediate in pharmaceutical and agrochemical synthesis. It delivers exceptional batch-to-batch consistency and structural fidelity—critical for multi-step asymmetric reactions where stereochemical integrity directly impacts final product efficacy and regulatory approval. This material is essential for R&D laboratories, contract development and manufacturing organizations (CDMOs), and fine chemical manufacturers engaged in the production of chiral active pharmaceutical ingredients (APIs) and advanced crop protection agents. Meosuc-Aapm-Pna CAS NO 70967-91-8 is supplied under strict quality governance to support GMP-aligned processes.

Application

• Synthesis of chiral β-lactam antibiotics (e.g., carbapenems and monobactams)
• Key building block in the manufacture of protease inhibitors for antiviral therapeutics
• Chiral auxiliary in asymmetric alkylation and aldol condensation reactions
• Intermediate for next-generation herbicidal amino acid analogs (e.g., phosphinothricin derivatives)
• Custom synthesis of labeled compounds for ADME and PET tracer development
• Development of enantioselective catalysts and ligands for industrial cross-coupling processes
• Process optimization studies requiring high-purity, low-metal-content intermediates
• Reference standard preparation for HPLC and LC-MS method validation in QC labs

Basic Information

Product Name	Meosuc-Aapm-Pna
CAS No.	70967-91-8
Molecular Formula	C12H15NO4
Molecular Weight	237.25 g/mol
Synonyms	(2R,3S)-2-(Methoxycarbonyl)-3-[(4-methoxyphenyl)amino]propanoic acid; Meosuc-AAPM-PNA; Methyl (2R,3S)-3-[(4-methoxyphenyl)amino]-2-(methoxycarbonyl)propanoate; (2R,3S)-3-(p-Anisidino)-2-methoxycarbonylpropionic acid; Methyl (2R,3S)-3-(p-methoxyanilino)-2-carbomethoxypropionate; Meosuc-AAPM; Methyl (2R,3S)-3-(4-methoxyphenylamino)-2-(methoxycarbonyl)propanoate; (2R,3S)-Methyl 3-(4-methoxyphenylamino)-2-(methoxycarbonyl)propanoate
EINECS	Not listed (not pre-registered under REACH)

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches are verified against stringent specifications including identity (IR, HPLC retention time match), assay (≥99.5% by HPLC), enantiomeric excess (≥99.0% ee by chiral HPLC), residual solvents (ICH Q3C compliant), and heavy metals (≤10 ppm total). Testing is performed in ISO/IEC 17025-accredited laboratories, supporting FDA, EMA, and PMDA regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at 15–25°C in a dry, well-ventilated area. Keep away from strong acid/organic solvent and fluoride/strong alkali environments. Due to its light-sensitive nature, minimize exposure to ambient and UV light during handling. Avoid repeated opening of container to prevent moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	99.5% – 100.5%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Related Substances (HPLC)	≤0.3% single impurity; ≤0.5% total impurities
Residual Solvents (GC)	MeOH ≤3000 ppm; Acetone ≤5000 ppm; ICH Q3C Class 3
Water (Karl Fischer)	≤0.2%
Sulfated Ash	≤0.1%
Heavy Metals (as Pb)	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.