Description

3-(2-Hydroxyethyl)Histidine is a modified amino acid derivative of L-histidine, featuring a hydroxyethyl group on the imidazole ring. This structural modification makes it a valuable building block and intermediate in advanced biochemical synthesis and pharmaceutical research. It is particularly relevant for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop novel peptides, enzyme inhibitors, or diagnostic agents.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of novel drug candidates, particularly those targeting histamine pathways or requiring modified amino acid backbones.
• Biochemical Research: Used as a specialized reagent in enzymatic studies, protein engineering, and metabolic pathway investigation.
• Peptide Synthesis: Serves as a unique, non-natural amino acid residue in the production of custom peptides for therapeutic and diagnostic applications.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Enzyme Inhibitor Development: Utilized in the research and development of selective inhibitors for enzymes that interact with histidine.

Basic Information

Product Name	3-(2-Hydroxyethyl)Histidine
CAS No.	70962-69-5
Molecular Formula	C8H13N3O3
Molecular Weight	199.21 g/mol
Synonyms	2-Hydroxyethylhistidine; 3-(2-Hydroxyethyl)-L-histidine; L-Histidine, 3-(2-hydroxyethyl)-; H-His(2-Hydroxyethyl)-OH; N(τ)-2-Hydroxyethylhistidine; 3-(2-Hydroxyethyl)-1H-imidazole-4-alanine; (2S)-2-Amino-3-[3-(2-hydroxyethyl)-1H-imidazol-4-yl]propanoic acid
EINECS	Contact for details

Quality Control

Our 3-(2-Hydroxyethyl)Histidine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.