Description

Fortimicin B is a potent aminoglycoside antibiotic complex member, valued for its broad-spectrum antibacterial activity against a range of Gram-negative and Gram-positive pathogens. Its significance lies in its role as a key intermediate and reference standard in pharmaceutical research and development, particularly for studying antibiotic mechanisms and resistance. This product is essential for research laboratories, analytical facilities, and manufacturers engaged in the synthesis and quality control of advanced antimicrobial agents.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for analytical methods, including HPLC, LC-MS, and microbiological assays to ensure product quality and regulatory compliance.
• Antibiotic Research & Development: Serves as a critical intermediate or active component in the R&D of novel aminoglycoside antibiotics and combination therapies.
• Microbiological Studies: Employed in in-vitro studies to investigate bacterial susceptibility, minimum inhibitory concentration (MIC) determination, and mechanisms of antibiotic action.
• Biochemical Research: Utilized in studies exploring protein synthesis inhibition and the interaction of aminoglycosides with ribosomal RNA.
• Quality Control & Assurance: Acts as a system suitability standard in pharmaceutical quality control laboratories to validate analytical procedures for antibiotic formulations.

Basic Information

Product Name	Fortimicin B
CAS No.	70952-84-0
Molecular Formula	C17H35N5O6
Molecular Weight	405.49 g/mol
Synonyms	Fortimicin B; Antibiotic XK-62-2; (2S,3R,4S,5S,6R)-5-Amino-2-[[(2S,3S,4R,5S)-5-amino-2-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]oxymethyl]-6-(1-hydroxyethyl)oxane-3,4-diol; Astromicin sulfate related compound B; Fortimicin B sulfate; KW-1070 related compound
EINECS	Contact for details

Quality Control

Every batch of Fortimicin B is manufactured and tested under strict quality management systems. We provide comprehensive analytical documentation to support your regulatory and research requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot, ensuring traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.