Description

Lhrh, Trp(7)- CAS NO 70920-44-4 is a synthetic peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH) with a specific tryptophan modification at position 7. This modification is critical for enhancing its binding affinity and metabolic stability, making it a valuable research and development tool. It is primarily utilized by pharmaceutical researchers and manufacturers in the development of advanced therapeutic agents, diagnostic assays, and in biochemical studies related to endocrinology and oncology.

Application

• Pharmaceutical R&D: Core intermediate in the synthesis of novel LHRH agonist and antagonist therapeutics for treating hormone-dependent cancers (e.g., prostate, breast) and reproductive disorders.
• Biochemical Research: Used as a high-purity reference standard and probe in receptor binding studies, signal transduction pathway analysis, and structure-activity relationship (SAR) investigations.
• Diagnostic Development: Serves as a key antigen or calibrator in the development of immunoassays and diagnostic kits for measuring hormone levels.
• Peptide Chemistry Studies: An important model compound for studying peptide stability, modification techniques, and advanced purification processes.

Basic Information

Product Name	Lhrh, Trp(7)-
CAS No.	70920-44-4
Molecular Formula	C₆₄H₈₃N₁₇O₁₂
Molecular Weight	1282.5 g/mol
Synonyms	Des-Gly10-LHRH ethylamide, Tryptorelin; [Des-Gly-NH210, Pro-NHEt9]-LHRH; Luteinizing Hormone-Releasing Hormone (6-10)-peptide ethylamide; LHRH Ethylamide; LHRH Agonist (Trp-7); P-Glu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt; Gonadorelin (6-10) ethylamide; Fertirelin acetate (related analog).
EINECS	Contact for details

Quality Control

Our Lhrh, Trp(7)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis, to ensure it meets stringent specifications for pharmaceutical research. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content (Amino Acid Analysis)	≥ 80.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.