Description

3-Amino-5-Fenyl-7-Methyl-1H-1,4-Benzodiazepine-2(3H)-On is a specialized benzodiazepine derivative, a key heterocyclic compound in advanced organic synthesis. This intermediate is valued for its precise molecular architecture, enabling the development of novel pharmacologically active molecules. It is primarily sought by research institutions and pharmaceutical developers engaged in creating new therapeutic agents and studying central nervous system (CNS) targets.

Application

• Pharmaceutical Intermediate: A critical building block in the research and development of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new compounds targeting GABA-A receptors and other CNS pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Preclinical Development: Employed in the synthesis of candidate compounds for pharmacological screening and early-stage drug development programs.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and the synthesis of complex organic molecules.
• Custom Synthesis: A starting material for the contract synthesis of specialized, non-commercial benzodiazepine derivatives for client-specific research projects.

Basic Information

Product Name	3-Amino-5-Fenyl-7-Methyl-1H-1,4-Benzodiazepine-2(3H)-On
CAS No.	70890-50-5
Molecular Formula	C₁₇H₁₅N₃O
Molecular Weight	277.32 g/mol
Synonyms	3-Amino-5-phenyl-7-methyl-1H-1,4-benzodiazepin-2(3H)-one; 3-Amino-5-phenyl-7-methyl-1,4-benzodiazepin-2-one; 70890-50-5; 5-Phenyl-7-methyl-3-amino-1,4-benzodiazepin-2-one; 3-Amino-5-phenyl-7-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Fenyl-7-Methyl-1H-1,4-Benzodiazepine-2(3H)-On is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.