Description

1-Fluoro-3-Phenylpropan-2-Amine is a versatile fluorinated amine building block of significant interest in advanced organic synthesis. Its value lies in the strategic incorporation of both a fluorine atom and a primary amine functional group, enabling precise modifications to molecular properties and reactivity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, including potential CNS-active molecules, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, where the fluorine atom can enhance biological activity, metabolic stability, and environmental profile.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and the effects of fluorine introduction on physicochemical properties like lipophilicity and metabolic stability.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value fluorinated specialty chemicals for various industrial applications.
• Material Science Precursor: Potential use in the synthesis of monomers or functional agents for advanced polymeric materials.

Basic Information

Product Name	1-Fluoro-3-Phenylpropan-2-Amine
CAS No.	70824-86-1
Molecular Formula	C9H12FN
Molecular Weight	153.20 g/mol
Synonyms	1-Fluoro-3-phenyl-2-propanamine; 2-Amino-1-fluoro-3-phenylpropane; (±)-1-Fluoro-3-phenylisopropylamine; 3-Phenyl-2-aminopropyl fluoride; 1-Fluoro-3-phenylpropan-2-ylamine; Benzenepropanamine, 1-fluoro-; α-(Aminomethyl)benzyl fluoride
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3-Phenylpropan-2-Amine is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistent quality suitable for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual ≤ 1.0%; Total ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.