Description

p-Morpholino-α-(Trifluoromethyl)Benzyl Alcohol is a high-value, fluorinated chiral building block and intermediate in organic synthesis. Its unique structure, featuring a morpholine ring and a trifluoromethylated benzylic alcohol, makes it a critical precursor for developing advanced pharmaceuticals and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides where the trifluoromethyl group improves lipophilicity and bioactivity.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and organocatalysts.
• Material Science Precursor: Intermediate for synthesizing specialty monomers and polymers with unique surface properties.
• Chemical Research & Development: Versatile starting material in academic and industrial R&D for exploring new synthetic methodologies and fluorinated compound libraries.

Basic Information

Product Name	p-Morpholino-α-(Trifluoromethyl)Benzyl Alcohol
CAS No.	70783-45-8
Molecular Formula	C12H14F3NO2
Molecular Weight	261.24 g/mol
Synonyms	4-Morpholino-α-(trifluoromethyl)benzenemethanol; 4-(Morpholin-4-yl)phenylmethanol; α-(Trifluoromethyl)-4-morpholinobenzyl Alcohol; 1-[4-(Morpholin-4-yl)phenyl]-2,2,2-trifluoroethanol; p-Morpholinyl-α-(trifluoromethyl)benzyl alcohol; 4-(Morpholin-4-yl)-α-(trifluoromethyl)benzyl alcohol; (4-Morpholinophenyl)(trifluoromethyl)methanol
EINECS	Contact for details

Quality Control

Our p-Morpholino-α-(Trifluoromethyl)Benzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess (if applicable), and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support compliance with relevant regulatory frameworks such as REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.