Description

Ethyl Glycochenodeoxycholate is a synthetic bile acid derivative, specifically the ethyl ester of glycochenodeoxycholic acid. This compound is of significant value in biochemical and pharmaceutical research due to its role as a key intermediate and reference standard for studying bile acid metabolism, membrane interactions, and receptor activity. It is primarily needed by research institutions, pharmaceutical developers, and diagnostic manufacturers working on hepatobiliary function, drug delivery systems, and metabolic disorder diagnostics.

Application

• Biochemical Research: Used as a critical reference standard and intermediate in studies of bile acid synthesis, transport, and signaling pathways.
• Pharmaceutical Development: Serves as a key starting material or intermediate in the synthesis of novel therapeutic agents targeting liver and metabolic diseases.
• Diagnostic Reagents: Employed in the formulation of calibrators and controls for in-vitro diagnostic kits measuring bile acid profiles.
• Cell Biology Studies: Utilized to investigate the effects of bile acids on cell membrane permeability, apoptosis, and cholestasis in vitro.
• Metabolomics: Acts as a defined metabolite standard for mass spectrometry and chromatography-based metabolic profiling.
• Academic Research: Fundamental tool for universities and research labs exploring gastroenterology, hepatology, and lipid metabolism.

Basic Information

Product Name	Ethyl Glycochenodeoxycholate
CAS No.	70779-05-4
Molecular Formula	C₂₈H₄₇NO₆
Molecular Weight	493.68 g/mol
Synonyms	Ethyl Glycochenodeoxycholate; N-[(3α,5β,7α)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine Ethyl Ester; Glycochenodeoxycholic Acid Ethyl Ester; Chenodeoxycholylglycine Ethyl Ester; Ethyl N-[(3α,5β,7α)-3,7-Dihydroxy-24-oxocholan-24-yl]glycinate; GCDCA Ethyl Ester; Ethyl 2-[(4R)-4-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11S,11aR)-7,11-Dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanamido]acetate
EINECS	Contact for details

Quality Control

Our Ethyl Glycochenodeoxycholate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.