Description

5-Ethyl-5-(Trimethylsilylmethyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized organosilicon pyrimidinetrione derivative, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in the unique reactivity imparted by the trimethylsilylmethyl group, which can be leveraged for selective transformations and as a protective strategy. This compound is primarily required by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those requiring silicon-containing moieties for enhanced metabolic stability or bioavailability.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the pyrimidinetrione core and silicon group can contribute to unique modes of action.
• Organosilicon Chemistry: Serves as a model compound or starting material for studying silyl group transfer reactions and the synthesis of silicon-functionalized heterocycles.
• Material Science Precursor: Potential use in the development of specialty polymers or coatings where silicon incorporation can modify material properties like thermal stability or surface characteristics.
• Academic & R&D Laboratories: Employed in methodological studies and the exploration of new synthetic pathways in organic and medicinal chemistry.

Basic Information

Product Name	5-Ethyl-5-(Trimethylsilylmethyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	70701-25-6
Molecular Formula	C10H18N2O3Si
Molecular Weight	242.35 g/mol
Synonyms	5-Ethyl-5-(trimethylsilylmethyl)barbituric acid; 5-Ethyl-5-(trimethylsilylmethyl)-1,3-diazinane-2,4,6-trione; 5-(Trimethylsilylmethyl)-5-ethylpyrimidine-2,4,6(1H,3H,5H)-trione; Trimethylsilylmethylbarbituric acid derivative; Silicon-functionalized barbiturate; TMSM-barbiturate
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-(Trimethylsilylmethyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC-MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.