Description

3-Chloro-L-Tyrosine is a halogenated derivative of the essential amino acid L-tyrosine, featuring a chlorine substituent on the aromatic ring. This modification makes it a valuable biochemical building block and research tool for studying enzyme mechanisms, protein modifications, and metabolic pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications ranging from proteomics to the synthesis of specialized compounds.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for tyrosine kinases, phosphatases, and halogenases.
• Proteomics & Mass Spectrometry: Serves as a stable isotope-labeled internal standard (e.g., 13C, 15N) for the accurate quantification of proteins and metabolites.
• Pharmaceutical Intermediates: Acts as a key chiral synthon in the research and development of novel therapeutic agents and diagnostic compounds.
• Metabolic Pathway Analysis: Employed to trace and understand tyrosine metabolism and chlorination processes in biological systems.
• Peptide Synthesis: Incorporated into custom peptides to study structure-activity relationships or to create peptides with modified properties.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, or NMR method development and validation.

Basic Information

Product Name	3-Chloro-L-Tyrosine
CAS No.	70680-93-2
Molecular Formula	C9H10ClNO3
Molecular Weight	215.63 g/mol
Synonyms	L-3-Chlorotyrosine; (2S)-2-Amino-3-(3-chloro-4-hydroxyphenyl)propanoic acid; 3-Chlorotyrosine; 3-Cl-Tyr; 3-Chloro-4-hydroxyphenylalanine; 3-Chloro-L-tyrosine; 3-Chlorotyrosine, L-; 3-CT
EINECS	Contact for details

Quality Control

Our 3-Chloro-L-Tyrosine is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications. For custom purity grades or specific impurity profiles, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	-15° to -20° (c=1 in 1N HCl)
Chiral Purity (HPLC)	≥99.0% L-isomer
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.