Description

Pyroglutamyl-Tyrosyl-Prolinamide is a synthetic tripeptide derivative of significant interest in advanced biochemical research and development. This compound serves as a crucial building block and reference standard for studying peptide interactions, stability, and biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuropeptide research, drug discovery, and the development of diagnostic assays. The high-purity material is essential for ensuring reproducible and reliable experimental results.

Application

• Neuropeptide Research: Used as a reference standard and synthetic analog in studies related to neuropeptide function and metabolism.
• Pharmaceutical R&D: Serves as a key intermediate or pharmacophore in the discovery and development of novel therapeutic agents targeting neurological pathways.
• Biochemical Assay Development: Employed in the calibration and validation of analytical methods such as HPLC and mass spectrometry for peptide quantification.
• Academic Research: A valuable tool for universities and research institutes investigating peptide chemistry, enzymology, and signal transduction mechanisms.
• Diagnostic Reagent Manufacturing: Can be utilized in the synthesis of components for specialized diagnostic kits and biosensors.

Basic Information

Product Name	Pyroglutamyl-Tyrosyl-Prolinamide
CAS No.	70650-88-3
Molecular Formula	C19H25N5O5
Molecular Weight	403.43 g/mol
Synonyms	pGlu-Tyr-Pro-NH2; L-Pyroglutamyl-L-tyrosyl-L-prolinamide; Pyr-Tyr-Pro-NH2; 5-Oxo-L-prolyl-L-tyrosyl-L-prolinamide; TRH Fragment (1-3); Thyrotropin-Releasing Hormone (1-3); pGlu-His-Pro-NH2 analog; Pyroglutamyltyrosylproline amide
EINECS	Contact for details

Quality Control

Our Pyroglutamyl-Tyrosyl-Prolinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination, mass spectrometry for identity confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.