Description

6-(4-Methylphenyl)-4-Oxo-2-Sulfanylidene-1,2,3,4-Tetrahydropyrimidine-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydropyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and high-value products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of dihydropyrimidinone (DHPM) derivatives and other bioactive molecules with potential therapeutic applications.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides due to its heterocyclic core structure.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing more complex nitrogen- and sulfur-containing heterocycles in medicinal chemistry.
• Chemical Research & Development: Employed in academic and industrial R&D labs for studying structure-activity relationships (SAR) and novel reaction pathways.
• Material Science Precursor: Investigated for potential use in the synthesis of organic electronic materials and specialty polymers.

Basic Information

Product Name	6-(4-Methylphenyl)-4-Oxo-2-Sulfanylidene-1,2,3,4-Tetrahydropyrimidine-5-Carbonitrile
CAS No.	70638-53-8
Molecular Formula	C13H11N3OS
Molecular Weight	257.31 g/mol
Synonyms	5-Cyano-6-(p-tolyl)-2-thioxo-1,2,3,4-tetrahydropyrimidin-4-one; 6-(4-Methylphenyl)-2-mercapto-4-oxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile; 6-(p-Tolyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile; 5-Cyano-2-mercapto-6-(4-methylphenyl)-4(1H)-pyrimidinone; DHPM Derivative; Biginelli Reaction Product
EINECS	Contact for details

Quality Control

Our production of 6-(4-Methylphenyl)-4-Oxo-2-Sulfanylidene-1,2,3,4-Tetrahydropyrimidine-5-Carbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.