Description

n-Formyl-Met-Leu-Phe Benzyl Ester is a synthetic tripeptide derivative, specifically a formylated chemotactic peptide analog. This compound is a critical biochemical tool for studying neutrophil activation and chemotaxis, serving as a potent agonist for the formyl peptide receptor (FPR). It is essential for researchers and manufacturers in the life sciences sector who require high-purity, well-characterized bioactive peptides for immunological research, drug discovery, and diagnostic assay development.

Application

• Biochemical Research: As a standard agonist for studying formyl peptide receptor (FPR) signaling pathways, neutrophil chemotaxis, and superoxide anion production.
• Immunology & Inflammation Studies: Used in in vitro and ex vivo assays to model and investigate inflammatory responses and immune cell activation.
• Drug Discovery & Screening: Serves as a reference compound and positive control in high-throughput screening (HTS) campaigns targeting FPR for anti-inflammatory therapeutics.
• Diagnostic Development: Utilized in the development and calibration of diagnostic kits and assays designed to measure neutrophil function or inflammatory markers.
• Cell Biology: Employed to induce controlled activation of phagocytic cells for studies on intracellular signaling, degranulation, and oxidative burst.
• Academic & Pharmaceutical R&D: A fundamental reagent for universities, research institutes, and pharmaceutical companies engaged in immunopharmacology and receptor biology.

Basic Information

Product Name	n-Formyl-Met-Leu-Phe Benzyl Ester
CAS No.	70637-32-0
Molecular Formula	C29H39N3O5S
Molecular Weight	541.70 g/mol
Synonyms	N-Formyl-Met-Leu-Phe-OBzl; fMLP Benzyl Ester; N-Formylmethionyl-leucyl-phenylalanine benzyl ester; For-Met-Leu-Phe-OBzl; Chemotactic Peptide fMLP-OBzl; Formyl-Met-Leu-Phe-O-Benzyl; N-Formyl-MLF-OBzl; Formyl-MLF-Benzyl Ester
EINECS	Contact for details

Quality Control

Our n-Formyl-Met-Leu-Phe Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.