Description

o-Methyl-D-Tyrosine Methyl Ester Hcl is a chiral, non-proteinogenic amino acid derivative, specifically engineered as a key synthetic intermediate. This compound matters for its role in the precise construction of complex peptides and active pharmaceutical ingredients (APIs), where stereochemical purity is critical. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in advanced peptide synthesis, drug discovery, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of peptide-based drugs and novel APIs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce modified tyrosine residues.
• Biochemical Research: Serves as a tool compound for studying enzyme mechanisms, receptor binding, and metabolic pathways.
• Proteomics & Labeling: Potential use in the preparation of isotopically labeled peptides for mass spectrometry analysis.
• Ligand Development: Employed in the design and synthesis of receptor ligands and enzyme inhibitors.
• Chiral Auxiliary: Utilized in asymmetric synthesis due to its defined D-configuration.

Basic Information

Product Name	o-Methyl-D-Tyrosine Methyl Ester Hcl
CAS No.	70601-64-8
Molecular Formula	C11H15NO3 • HCl
Molecular Weight	245.70 g/mol (Free base: 209.24 g/mol)
Synonyms	D-2-Methyltyrosine Methyl Ester Hydrochloride; Methyl (2R)-2-amino-3-(2-hydroxy-5-methylphenyl)propanoate hydrochloride; (R)-2-Amino-3-(2-hydroxy-5-methylphenyl)propionic acid methyl ester hydrochloride; H-D-2-MeTyr-OMe • HCl; D-o-Methyltyrosine Methyl Ester HCl; D-2-Methyltyrosine Methyl Ester HCl; (R)-2-Methyltyrosine Methyl Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our o-Methyl-D-Tyrosine Methyl Ester Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.