Description

Ac-D-Tyr(Me)-Oh is a protected, non-natural amino acid derivative, specifically the N-acetylated, O-methylated form of D-tyrosine. This compound is a crucial chiral building block in advanced organic synthesis, particularly for the development of peptides and peptidomimetics with enhanced metabolic stability and specific biological activity. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, specialized intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of novel therapeutic peptides and protease inhibitors.
• Peptide Synthesis: Used in Solid-Phase Peptide Synthesis (SPPS) and solution-phase methods to incorporate modified tyrosine residues.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides or affinity probes for biochemical assays.
• Academic & Industrial Research: A valuable tool in medicinal chemistry for studying structure-activity relationships (SAR) and peptide backbone modifications.
• Fine Chemical Production: Employed in the multi-step synthesis of complex organic molecules requiring protected amino acid motifs.

Basic Information

Item	Details
Product Name	Ac-D-Tyr(Me)-Oh
CAS No.	70601-62-6
Molecular Formula	C₁₂H₁₅NO₄
Molecular Weight	237.25 g/mol
Synonyms	N-Acetyl-D-O-methyltyrosine; Ac-D-Tyr(OMe)-OH; (R)-2-Acetamido-3-(4-methoxyphenyl)propanoic acid; N-Acetyl-3-(4-methoxyphenyl)-D-alanine; D-N-Acetyl-O-methyltyrosine; Ac-D-Tyr(Me)-OH; Ac-D-Tyr(OMe)-OH
EINECS	Contact for details

Quality Control

Our Ac-D-Tyr(Me)-Oh is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR, MS). A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.