Description

(2R)-2-Amino-3-[(2R)-2-Amino-3-(Carboxymethylamino)-3-Oxopropyl]Disulfanylpropanoic Acid is a specialized chiral compound featuring a disulfide bridge and a carboxymethylamino moiety, making it a valuable building block for advanced synthesis. This high-purity intermediate is critical for ensuring the structural integrity and biological activity of complex peptide-based pharmaceuticals. It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutics, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of complex peptide drugs and therapeutic agents.
• Bioconjugation Reagent: Used in the development of antibody-drug conjugates (ADCs) and protein labeling due to its reactive disulfide group.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzyme inhibition research.
• Peptide Synthesis: Essential for constructing peptides with specific disulfide linkages that are crucial for correct protein folding and stability.
• Diagnostic Agent Development: Utilized in creating contrast agents or probes for molecular imaging and diagnostic assays.
• Ligand Synthesis: For the preparation of chelating agents or ligands used in metal catalysis or radiopharmaceuticals.

Basic Information

Product Name	(2R)-2-Amino-3-[(2R)-2-Amino-3-(Carboxymethylamino)-3-Oxopropyl]Disulfanylpropanoic Acid
CAS No.	70555-24-7
Molecular Formula	C9H16N4O5S2
Molecular Weight	324.37 g/mol
Synonyms	N-[2-[[(2R)-2-Amino-1-carboxyethyl]dithio]-1-[(carboxymethyl)carbamoyl]ethyl]glycine; L-Cystine, N-[N-(carboxymethyl)glycyl]-; (R)-2-Amino-3-((R)-2-amino-3-(carboxymethylamino)-3-oxopropyl)disulfanyl)propanoic acid; Glycine, N-[2-[[(2R)-2-amino-1-carboxyethyl]dithio]-1-[(carboxymethyl)carbamoyl]ethyl]-; A building block for glutathione analogues; A chiral disulfide amino acid derivative
EINECS	Contact for details

Quality Control

Our (2R)-2-Amino-3-[(2R)-2-Amino-3-(Carboxymethylamino)-3-Oxopropyl]Disulfanylpropanoic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and cGMP applications. All materials are supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant ICH guidelines and can supply material that meets custom specifications for chiral purity and heavy metal content upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.