Description

n-α-Palmitoyl-S-[2,3-Bis(Palmitoyloxy)-(2Rs)-Propyl]-L-Cysteine is a synthetic lipopeptide derivative, structurally related to the immunostimulatory S-[2,3-bis(palmitoyloxy)propyl]cysteine (Pam2Cys) moiety. This compound is a key intermediate and functional molecule in advanced pharmaceutical and immunological research. It is primarily utilized for the development of novel vaccine adjuvants and immunomodulatory drug delivery systems. Researchers and manufacturers in the biopharmaceutical sector require this high-purity material for its role in enhancing immune responses and creating targeted therapeutic formulations.

Application

• Vaccine Adjuvant Development: As a synthetic analog of bacterial lipopeptides, it is a critical component in the research and formulation of next-generation vaccine adjuvants to potentiate immune responses.
• Immunomodulator Synthesis: Serves as a key building block for synthesizing Toll-like receptor 2 (TLR2) agonists and other immunostimulatory compounds.
• Lipidated Peptide Conjugation: Used to introduce palmitoyl groups onto peptides or proteins, creating lipopeptides for enhanced cellular uptake and stability.
• Drug Delivery Systems: Incorporated into liposomes, nanoparticles, and other nanocarriers to create targeted delivery systems with immunostimulatory properties.
• Bioconjugation & Labeling: Employed in biochemical research for the site-specific lipid conjugation of biomolecules.
• Pharmaceutical Intermediates: Acts as a high-value intermediate in the multi-step synthesis of complex active pharmaceutical ingredients (APIs) with immunotherapeutic functions.

Basic Information

Item	Details
Product Name	n-α-Palmitoyl-S-[2,3-Bis(Palmitoyloxy)-(2Rs)-Propyl]-L-Cysteine
CAS No.	70512-46-8
Molecular Formula	C42H79NO7S
Molecular Weight	742.15 g/mol
Synonyms	Pam2Cys-Palm; N-Palmitoyl-S-[2,3-bis(palmitoyloxy)propyl]cysteine; S-[2,3-Bis(palmitoyloxy)propyl]-N-palmitoylcysteine; Lipopeptide Pam2Cys-Palmitoyl; TLR2 Agonist Lipopeptide Derivative; N-Palmitoyl-Pam2Cys; (R)-N-Palmitoyl-S-[2,3-bis(palmitoyloxy)propyl]cysteine; Synthetic Lipopeptide 70512-46-8
EINECS	Contact for details

Quality Control

Our n-α-Palmitoyl-S-[2,3-Bis(Palmitoyloxy)-(2Rs)-Propyl]-L-Cysteine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, as the compound is easily oxidized. For short-term use, store desiccated at 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.