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1-Phenyl-1-[3-(Trifluoromethyl)Phenyl]Methanamine CAS NO 70428-92-1


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CAS No.:70428-92-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Phenyl-1-[3-(Trifluoromethyl)Phenyl]Methanamine is a high-value trifluoromethylated aromatic amine building block, prized for its ability to impart unique physicochemical properties to advanced molecular architectures. Its core value lies in the combination of a robust amine functional group with the electron-withdrawing and lipophilicity-enhancing trifluoromethyl group, making it a critical intermediate for performance-driven applications. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients and functional polymers.

Application

  • Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) drugs, kinase inhibitors, and anti-inflammatory agents.
  • Agrochemical Synthesis: Used in the research and manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
  • Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis and fine chemical manufacturing.
  • Advanced Material Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials requiring tailored electronic and solubility characteristics.
  • Chemical Research & Development: A versatile building block for medicinal chemistry, process chemistry, and discovery research in academic and industrial laboratories.

Basic Information

Product Name 1-Phenyl-1-[3-(Trifluoromethyl)Phenyl]Methanamine
CAS No. 70428-92-1
Molecular Formula C14H12F3N
Molecular Weight 251.25 g/mol
Synonyms [3-(Trifluoromethyl)phenyl](phenyl)methanamine; α-Phenyl-3-(trifluoromethyl)benzylamine; Benzenemethanamine, α-phenyl-3-(trifluoromethyl)-; 1-Phenyl-1-[3-(trifluoromethyl)phenyl]methylamine; (3-Trifluoromethylphenyl)(phenyl)methanamine; 3-Trifluoromethylbenzhydrylamine; 1-(3-Trifluoromethylphenyl)-1-phenylethylamine (common misnomer); α-(3-Trifluoromethylphenyl)benzylamine
EINECS Contact for details

Quality Control

Our 1-Phenyl-1-[3-(Trifluoromethyl)Phenyl]Methanamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP, ISO, and other relevant regulatory frameworks for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and moisture. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0% (Standard Grade)
Purity (GC) ≥ 97.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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