Description

H-Gly-Lys-His-Oh CAS NO 70253-66-6 is a synthetic tripeptide composed of the amino acids glycine, lysine, and histidine. This compound is of significant interest in biochemical research and pharmaceutical development due to its potential role as a bioactive peptide or a building block for more complex peptide structures. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in peptide synthesis, drug discovery, and the study of enzymatic processes.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis of novel therapeutic peptides and peptidomimetics.
• Biochemical Studies: Used as a substrate or inhibitor in enzymatic assays to study protease activity and peptide metabolism.
• Cosmetic & Dermatological Applications: Investigated for potential use in anti-aging or skin-repair formulations due to the presence of amino acids involved in collagen synthesis.
• Nutritional Science: Studied as a potential bioactive component in specialized nutraceuticals or dietary supplements.
• Academic Research: Employed in universities and laboratories for fundamental research in peptide chemistry, structure-activity relationships (SAR), and molecular biology.
• Process Development: Acts as a model compound for optimizing large-scale peptide synthesis and purification techniques.

Basic Information

Product Name	H-Gly-Lys-His-Oh
CAS No.	70253-66-6
Molecular Formula	C14H25N7O5
Molecular Weight	371.39 g/mol
Synonyms	Glycyl-L-lysyl-L-histidine; GKH; H-Gly-Lys-His-OH tripeptide; L-Histidyl-L-lysylglycine; Gly-Lys-His; GK-H; GK-H Peptide; Tripeptide-1 (cosmetic ingredient name)
EINECS	Contact for details

Quality Control

Our H-Gly-Lys-His-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and chiral analysis to ensure the correct stereochemistry. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a desiccated environment to prevent moisture absorption, which can lead to degradation or clumping. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Amino Acid Composition	Conforms to theoretical ratio
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.