Description

n-Formylglutathione is a key biochemical intermediate involved in the metabolism of formaldehyde and other one-carbon units. This compound matters significantly in research and development for its role in enzymatic pathways, particularly those involving glutathione-dependent formaldehyde dehydrogenase. Industries requiring advanced biochemical research, including pharmaceutical development, toxicology studies, and enzymology, need this high-purity intermediate for their investigative and synthetic processes.

Application

• Biochemical Research: Critical intermediate for studying the glutathione-dependent formaldehyde dehydrogenase (FDH) pathway and one-carbon metabolism.
• Enzymology Studies: Used as a substrate or reference standard in enzyme kinetics and mechanism studies related to formaldehyde detoxification.
• Pharmaceutical R&D: Serves as a building block or reference compound in the development of drugs targeting metabolic disorders or detoxification pathways.
• Toxicology & Metabolism Research: Employed in studies investigating the metabolic fate of formaldehyde and the protective role of the glutathione system.
• Diagnostic Reagent Development: Potential use in formulating assay kits for measuring formaldehyde or related enzyme activities in biological samples.
• Academic Research: Essential for universities and research institutes focusing on biochemistry, molecular biology, and cellular metabolism.

Basic Information

Product Name	n-Formylglutathione
CAS No.	70239-28-0
Molecular Formula	C11H16N3O8S
Molecular Weight	350.33 g/mol
Synonyms	N-Formylglutathione; S-Formylglutathione; Glutathione, S-formyl-; L-Glutathione, S-formyl-; (2S)-2-Amino-5-[[(2R)-1-(carboxymethylamino)-3-(formylsulfanyl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid; Formylglutathione; FGSH; NSC 334153
EINECS	Contact for details

Quality Control

Our n-Formylglutathione is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.