Description

2-(tert-Butyl)-4-Chloro-5-Nitropyrimidine is a high-value pyrimidine derivative, a crucial nitrogen-containing heterocyclic building block in advanced organic synthesis. Its core value lies in its dual functionalization, providing reactive handles for the construction of complex molecular architectures. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its pyrimidine core.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, dyes, and photoactive compounds.
• Chemical Biology: Employed in the synthesis of molecular probes and labeled compounds for biochemical studies.
• Academic & R&D: A versatile reagent for methodological development in organic chemistry and heterocyclic chemistry.

Basic Information

Product Name	2-(tert-Butyl)-4-Chloro-5-Nitropyrimidine
CAS No.	70227-50-8
Molecular Formula	C8H10ClN3O2
Molecular Weight	215.64 g/mol
Synonyms	4-Chloro-2-tert-butyl-5-nitropyrimidine; 2-tert-Butyl-4-chloro-5-nitropyrimidine; 4-Chloro-5-nitro-2-(1,1-dimethylethyl)pyrimidine; 5-Nitro-4-chloro-2-tert-butylpyrimidine; 2-(1,1-Dimethylethyl)-4-chloro-5-nitropyrimidine; 4-Chloro-2-(tert-butyl)-5-nitropyrimidine; tert-Butyl 4-chloro-5-nitropyrimidine-2-yl ether (incorrect but common search term); Pyrimidine, 4-chloro-2-(1,1-dimethylethyl)-5-nitro-
EINECS	Contact for details

Quality Control

Our 2-(tert-Butyl)-4-Chloro-5-Nitropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.