Description

Lhrh, Pglu(1)-Phe(2)-Trp(3)-Lys(6)- is a synthetic peptide analog of Gonadotropin-Releasing Hormone (GnRH). This compound is of significant interest for its role in modulating the hypothalamic-pituitary-gonadal axis, making it a critical research tool and a potential precursor for therapeutic development. It is primarily utilized by pharmaceutical research organizations, biotechnology companies, and academic institutions engaged in endocrinology, oncology, and reproductive medicine studies.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of hormone-related therapies.
• Endocrinology Studies: Used in vitro and in vivo to investigate the regulation of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion.
• Oncology Research: Explored in studies targeting hormone-dependent cancers, such as prostate and breast cancer, due to its action on gonadal steroid production.
• Reproductive Medicine: Applied in research concerning fertility treatments, contraception, and disorders of the reproductive system.
• Biochemical Assays: Employed as a ligand in receptor binding studies and competitive immunoassays to understand GnRH receptor interactions.
• Peptide Chemistry & Synthesis: Used as a building block or intermediate for the synthesis of more complex GnRH analogs and conjugates.

Basic Information

Product Name	Lhrh, Pglu(1)-Phe(2)-Trp(3)-Lys(6)-
CAS No.	70204-28-3
Molecular Formula	C58H78N16O12
Molecular Weight	1151.34 g/mol
Synonyms	GnRH (4-10), Luteinizing Hormone-Releasing Hormone (4-10); Pglu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 (4-10 fragment); Des-Gly10, Pro9-ethylamide-GnRH (4-10); [pGlu1, Phe2, Trp3, Lys6]-LHRH; Gonadorelin (4-10) fragment; LHRH agonist fragment; Luteinising Hormone Releasing Hormone analog.
EINECS	Contact for details

Quality Control

Our Lhrh, Pglu(1)-Phe(2)-Trp(3)-Lys(6)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure compliance with high-purity research-grade standards. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPIC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.