Description

Ddz-Lys(Z)-Oh is a protected amino acid derivative widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precision. It is primarily utilized in pharmaceutical R&D, biotechnology, and academic laboratories for the development of novel therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of lysine residues with orthogonal protecting groups.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for constructing peptide fragments.
• Pharmaceutical Research: Serves as a building block in the development of peptide-based drugs, hormones, and diagnostic agents.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins due to its selectively protected side chain.
• Combinatorial Chemistry: Employed in libraries for drug discovery to explore structure-activity relationships.
• Academic & Biochemical Studies: Used in research to study protein-protein interactions and enzyme mechanisms.

Basic Information

Product Name	Ddz-Lys(Z)-Oh
CAS No.	70082-80-3
Molecular Formula	C₂₀H₂₂N₂O₆
Molecular Weight	386.40 g/mol
Synonyms	Nα-(2,4-Dimethoxybenzyl)-Nε-carbobenzyloxy-L-lysine; Nα-Ddz-Nε-Z-L-lysine; (2S)-6-[[(Benzyloxy)carbonyl]amino]-2-[(2,4-dimethoxybenzyl)amino]hexanoic acid; Ddz-Lys(Z)-OH; Ddz-Lys(Z); Fmoc-Lys(Z)-OH alternative; Ddz-protected lysine derivative; Orthogonally protected lysine
EINECS	Contact for details

Quality Control

Our Ddz-Lys(Z)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	[α]²⁰D: Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.