Description

(Gly0)-Met-Enkephalin CAS NO 70013-23-9 is a synthetic peptide analog of the endogenous opioid peptide Met-Enkephalin, modified at the N-terminus. This compound is a critical research tool for studying opioid receptor pharmacology, signal transduction, and the physiological roles of enkephalins in pain modulation and neurological function. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuroscience, analgesic drug discovery, and peptide chemistry.

Application

• Neuroscience Research: Used as a reference standard and active ligand in studies of delta (δ) and mu (μ) opioid receptor binding, activation, and downstream effects.
• Pharmacological Assays: Serves as a key compound in vitro and in vivo assays to investigate analgesic pathways, tolerance, and dependence mechanisms.
• Drug Discovery & Development: Acts as a lead compound or intermediate for the design and synthesis of novel peptide-based analgesics with potentially improved stability or receptor selectivity.
• Biochemical Studies: Employed in enzymatic stability tests and metabolic studies to understand the degradation pathways of enkephalin-related peptides.
• Cell Signaling Research: Utilized to probe G-protein coupled receptor (GPCR) signaling cascades and intracellular second messenger systems activated by opioid receptors.

Basic Information

Product Name	(Gly0)-Met-Enkephalin
CAS No.	70013-23-9
Molecular Formula	C28H37N5O7S
Molecular Weight	587.69 g/mol
Synonyms	Glycyl-methionine enkephalin; H-Gly-Tyr-Gly-Gly-Phe-Met-OH; [Gly0]-Met-Enkephalin; Gly-Met-Enkephalin; Opioid peptide fragment; YGGFM (single-letter abbreviation); Tyr-Gly-Gly-Phe-Met (with N-terminal Gly); (Gly0)-Methionine Enkephalin
EINECS	Contact for details

Quality Control

Our (Gly0)-Met-Enkephalin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. We provide Certificates of Analysis (COA) with detailed specifications for traceability and assurance. The product is suitable for research and development applications requiring high-purity peptide standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, DMSO, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.