Description

Boc-Ser(Ac)-Oh Dcha CAS NO 7801-80-1 is a protected amino acid derivative, specifically the tert-butoxycarbonyl (Boc) and acetyl (Ac) protected form of serine, supplied as a dicyclohexylamine (DCHA) salt. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), offering enhanced stability and solubility for complex peptide chain assembly. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptide hormones, and biochemical research reagents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled, sequential addition of serine residues during automated or manual peptide synthesis.
• Pharmaceutical Research & Development: Used in the discovery and production of peptide-based active pharmaceutical ingredients (APIs) for therapeutic applications.
• Bioconjugation and Labeling: Serves as a modified serine source for introducing specific functional groups or labels into peptides and proteins.
• Biochemical Research: Employed in studying enzyme-substrate interactions, protein folding, and structure-activity relationships (SAR) where a protected serine moiety is required.
• Combinatorial Chemistry Libraries: A valuable component for generating diverse libraries of peptide analogs for high-throughput screening.

Basic Information

Item	Detail
Product Name	Boc-Ser(Ac)-Oh Dcha
CAS No.	7801-80-1
Molecular Formula	C20H36N2O6
Molecular Weight	400.51 g/mol
Synonyms	Boc-Ser(Ac)-OH·DCHA; N-α-(tert-Butoxycarbonyl)-O-acetyl-L-serine dicyclohexylamine salt; Boc-L-Ser(Ac)-OH DCHA salt; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-acetyloxypropanoic acid - N-cyclohexylcyclohexanamine (1:1); Boc-Ser(OAc)-OH·DCHA; tert-Butyloxycarbonyl-O-acetyl-L-serine dicyclohexylammonium salt; N-Boc-O-acetyl-L-serine DCHA salt
EINECS	Contact for details

Quality Control

Our Boc-Ser(Ac)-Oh Dcha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, specific optical rotation measurement, and identity confirmation (IR, NMR) to ensure it meets the high standards required for peptide synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	-10.0° to -14.0° (c=1 in DMF)
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.