Description

Z-Pro-Leu-Gly-Oh is a synthetic tripeptide derivative, specifically a protected peptide sequence. This compound serves as a crucial building block and intermediate in advanced organic synthesis and peptide research. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on developing novel therapeutic agents and studying biochemical pathways.

Application

• Pharmaceutical Intermediate: Used in the synthesis of more complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Serves as a model compound or substrate in enzymatic studies and proteomics research.
• Peptide Library Construction: A key component in solid-phase and solution-phase peptide synthesis for creating diverse peptide libraries for screening.
• Protease/Enzyme Substrate: Potential use as a substrate for studying the activity and specificity of proteolytic enzymes like collagenases or other peptidases.
• Chemical Biology Tool: Employed in the development of probes and inhibitors to study cell signaling and protein-protein interactions.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Z-Pro-Leu-Gly-Oh
CAS No.	7801-38-9
Molecular Formula	C20H27N3O6
Molecular Weight	405.45 g/mol
Synonyms	Z-Pro-Leu-Gly-OH; N-Carbobenzoxy-Prolyl-Leucyl-Glycine; CBZ-Pro-Leu-Gly-OH; Benzyloxycarbonyl-Pro-Leu-Gly-OH; Nα-Cbz-L-Prolyl-L-Leucyl-Glycine; Z-L-Pro-L-Leu-Gly-OH; (S)-2-(((S)-1-((S)-2-((Benzyloxy)carbonylamino)-1-oxopropan-2-yl)pyrrolidine-2-carboxamido)-4-methyl-1-oxopentan-2-yl)amino)acetic acid; CBZ-Pro-Leu-Gly
EINECS	Contact for details

Quality Control

Our Z-Pro-Leu-Gly-Oh is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality system is designed to support cGMP compliance for use in research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.