Description

Z-Gly-Tyr-Oh CAS NO 7801-35-6 is a protected dipeptide building block, specifically the benzyloxycarbonyl (Z) derivative of glycyl-tyrosine. This compound is a critical intermediate in solid-phase peptide synthesis (SPPS), enabling the controlled elongation of peptide chains with high fidelity. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used in academic and industrial R&D for studying enzyme-substrate interactions, protein folding, and signal transduction pathways.
• Peptide Library Synthesis: A fundamental component in combinatorial chemistry for creating diverse peptide libraries used in drug discovery and screening.
• API Development: Serves as a precursor in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) containing tyrosine-glycine sequences.
• Proteomics & Diagnostics: Employed in the preparation of labeled peptides and standards for mass spectrometry and diagnostic assays.

Basic Information

Product Name	Z-Gly-Tyr-Oh
CAS No.	7801-35-6
Molecular Formula	C19H20N2O6
Molecular Weight	372.37 g/mol
Synonyms	N-CBZ-Glycyl-L-tyrosine; Z-Gly-Tyr-OH; CBZ-Gly-Tyr-OH; Nα-Carbobenzoxy-glycyl-L-tyrosine; Benzyl N-[(benzyloxy)carbonyl]glycyl-L-tyrosinate; Glycine, N-[(phenylmethoxy)carbonyl]-, L-tyrosyl-; (2S)-2-[[2-[(phenylmethoxy)carbonylamino]acetyl]amino]-3-(4-hydroxyphenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our Z-Gly-Tyr-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for peptide synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in GMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	-10.0° to -15.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.