Description

1-Naphthylalanine is a specialized non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial chiral building block for the development of novel peptide-based therapeutics and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, asymmetric synthesis, and the development of enzyme inhibitors or receptor ligands.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used to incorporate naphthyl groups into peptide backbones to modulate biological activity, stability, and receptor binding affinity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new pharmacophores and develop enzyme inhibitors.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material for the preparation of enantiomerically pure compounds.
• Biochemical Probes: Useful in the design of fluorescent or affinity probes for studying biological systems and protein interactions.
• Material Science: Potential precursor for specialized polymers or organic electronic materials requiring specific aromatic functionalities.

Basic Information

Product Name	1-Naphthylalanine
CAS No.	7758-42-1
Molecular Formula	C₁₃H₁₃NO₂
Molecular Weight	215.25 g/mol
Synonyms	1-Naphthylalanine; (S)-2-Amino-3-(naphthalen-1-yl)propanoic acid; 1-Nal; L-1-Naphthylalanine; α-Amino-1-naphthalenepropanoic acid; Naphthalene-1-alanine; 1-Naphthalenealanine; (S)-1-Naphthylalanine
EINECS	Contact for details

Quality Control

Our 1-Naphthylalanine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC and chiral analysis, to verify identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.