Description

5-Iodo-6-Methylpyrimidin-4-Ol is a halogenated pyrimidine derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its functionalized structure, which allows for selective cross-coupling reactions and further derivatization, making it a critical intermediate for creating complex molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting nucleoside analogs and enzyme inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its pyrimidine core.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce the iodopyrimidine moiety into more complex molecular architectures.
• Material Science Research: Investigated as a monomer or functional unit in the design of organic electronic materials and specialty polymers.
• Chemical Biology Probe Development: Utilized to create tagged molecules for studying biological processes and protein interactions.

Basic Information

Product Name	5-Iodo-6-Methylpyrimidin-4-Ol
CAS No.	7752-74-1
Molecular Formula	C5H5IN2O
Molecular Weight	236.01 g/mol
Synonyms	4-Hydroxy-5-iodo-6-methylpyrimidine; 5-Iodo-6-methyl-4-pyrimidinol; 6-Methyl-5-iodopyrimidin-4-ol; 5-Iodo-6-methyl-4(1H)-pyrimidinone; 5-Iodo-6-methyl-4-hydroxypyrimidine; 4(1H)-Pyrimidinone, 5-iodo-6-methyl-
EINECS	Contact for details

Quality Control

Our 5-Iodo-6-Methylpyrimidin-4-Ol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.